Extended Data Fig. 5: Relative AGO1 and AGO2 binding ratio of ACTB sdRNA compared to its precursor. | Nature

Extended Data Fig. 5: Relative AGO1 and AGO2 binding ratio of ACTB sdRNA compared to its precursor.

From: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52

Extended Data Fig. 5

a, b, BRCA1 RIP analyses of ACTB sdRNA or its precursor, showing the raw data as a percentage of input (a) or as the fold change of the signal obtained between the relevant BRCA1 antibody and a beads-only control (b). c, RIP analysis showing the binding ratio (log2-transformed) between ACTB sdRNA and its precursor (quantified using TaqMan and strand-specific reverse transcription followed by qPCR) after AGO1 or AGO2 immunoprecipitation/RIP from HeLa whole-cell extracts.

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