Extended Data Fig. 8: β-HPV viral load is markedly reduced in skin cancer cells compared to their adjacent normal skin in immunocompetent patients. | Nature

Extended Data Fig. 8: β-HPV viral load is markedly reduced in skin cancer cells compared to their adjacent normal skin in immunocompetent patients.

From: Immunity to commensal papillomaviruses protects against skin cancer

Extended Data Fig. 8

a, Representative DNA ISH of a wart, hypertrophic actinic keratosis arising in association with a wart (HAK in verruca), SCC in immunosuppressed patients and an SCC in an immunocompetent patient. Scale bars, 100 μm. b, c, Quantification of β-HPV DNA ISH signals in paired samples of skin cancer and the adjacent normal skin from immunosuppressed patients (b; n = 10) and immunocompetent patients (c; n = 10) (two-tailed Wilcoxon matched-pairs signed-rank test).

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