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Note that SU-DIPG-XIII-P∗ and SU-DIPG-XIII-FL were tissue samples acquired from the same patient at autopsy; in this case the pontine tumour (P) received focal radiotherapy, whereas the frontal lobe (FL) tumour was an untreated metastasis from the primary pontine tumour to the frontal lobe. DIPG, diffuse intrinsic pontine glioma; GBM, glioblastoma; HGG, high-grade glioma; TMZ, temozolomide; WHO, World Health Organization; XRT, radiotherapy.