Author Correction | Published:

Author Correction: Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury

Nature (2019) | Download Citation


Correction to Nature, published online 28 November 2018.

In Fig. 1j of this Letter, one data point was inadvertently omitted from the graph during reformatting for publication for the acute kidney injury (AKI), double knockout (−/−), S-nitrosothiol (SNO) condition at a nitrosylation level of 25.9 pmol mg−1, and the legend stated that statistical significance was assessed using one-way analysis of variance (ANOVA) with Tukey’s post hoc test, but in fact the value originally shown (P = 0.0221) was determined by Fisher’s test. Analysis of these data using Tukey’s test after instrument normalization for test-day (as per original experimental design; see the original Supplementary Information) yields a significance value of P = 0.0032. The Supplementary Information for this Amendment contains the originally published Source Data for Fig. 1j sorted by test-day. These changes do not affect the conclusions of this experiment. Figure 1 of the original Letter and its Source Data have been corrected online.

Fig. 1: This figure shows the original Fig. 1j (with missing data point, and analysed using Fisher’s test) and the corrected Fig. 1j (with data point added and analysed using Tukey’s test).
Fig. 1

WT, wild-type. The normalized ratio of 1 represents approximately 7 pmol mg−1 SNO.

Supplementary information is available in the online version of this Amendment.

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Author notes

  1.  These authors contributed equally: Rongli Zhang, Puneet Anand.


  1. Institute for Transformative Molecular Medicine, Department of Medicine, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, OH, USA

    • Hua-Lin Zhou
    • , Rongli Zhang
    • , Puneet Anand
    • , Colin T. Stomberski
    • , Zhaoxia Qian
    • , Alfred Hausladen
    •  & Jonathan S. Stamler
  2. Center for Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, OH, USA

    • Liwen Wang
  3. Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

    • Eugene P. Rhee
  4. Broad Institute of MIT and Harvard, Cambridge, MA, USA

    • Eugene P. Rhee
  5. Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA

    • Samir M. Parikh
    •  & S. Ananth Karumanchi
  6. Center for Vascular Biology Research, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA

    • Samir M. Parikh
    •  & S. Ananth Karumanchi
  7. Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA

    • S. Ananth Karumanchi
  8. Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA

    • Jonathan S. Stamler


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Correspondence to Jonathan S. Stamler.

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