Extended Data Fig. 8: In vivo decay rates of cells with intact and defective proviruses. | Nature

Extended Data Fig. 8: In vivo decay rates of cells with intact and defective proviruses.

From: A quantitative approach for measuring the reservoir of latent HIV-1 proviruses

Extended Data Fig. 8

The frequency of cells carrying intact proviruses, proviruses with 3′ deletion and/or hypermutation (3′ del/hyper), and proviruses with 5′ deletions (5′ del) was measured in resting CD4+ T cells from patients on long-term suppressive ART. Data are plotted in terms of decay rate assuming exponential decay. Half-life values for the same decay curves are shown in Fig. 4c. Negative decay rate indicates proliferation.

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