Extended Data Fig. 2: Aβ plaques and CAA in AppNL-F/NL-F mice following inoculation with c-hGH preparations. | Nature

Extended Data Fig. 2: Aβ plaques and CAA in AppNL-F/NL-F mice following inoculation with c-hGH preparations.

From: Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone

Extended Data Fig. 2

AppNL-F/NL-F mice were inoculated with c-hGH batch HWP 42 (a, cf, kn) or HWP 51 (b, gj, or) and culled after 240 days. Aβ deposition was assessed on sagittal sections (a, b). Black and red boxes denote areas magnified to better show cerebellar Aβ deposits (cj) and CAA (kr), respectively, in the middle and lower panels. Scale bars represent 1.1 mm for whole sections (a, b) and 50 µm for the cerebellar region and CAA (cr).

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