Related to Fig. 3. a, Myoblast (left), myotube (middle) and shared (right) connectome analysis for all TDP-43 eCLIP peaks (top) and TDP-43 exonic peaks (bottom). b, TDP-43 binds predominantly to exons of protein-coding RNAs in C2C12 myoblasts. c, Peak distribution for significantly enriched TDP-43 peak locations in myoblasts and myotubes across the transcriptome reveal increased exonic and 3′-UTR associations compared to previously identified neuronal TDP-43 peaks18,19. d, Identification of multiple TDP-43-binding sites across and within exons of Ttn. The zoomed region is representative of multiple UG-rich sequences within a single exon. n = 3 biologically independent experiments, each showing similar results.