Retraction | Published:

Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Naturevolume 561page420 (2018) | Download Citation

Retraction to: Nature https://doi.org/10.1038/nature10167, published online 13 July 2011; corrected online 25 January 2012; corrected online 16 September 2015.

This Letter is being retracted owing to issues with Fig. 1d and Supplementary Fig. 31b, and the unavailability of original data for these figures, which raises concerns regarding the integrity of the figures. Nature published two previous corrections related to this Letter1,2. These issues in aggregate undermine the confidence in the integrity of this study. Authors Michael Foley, Monica Schenone, Nicola J. Tolliday, Todd R. Golub, Steven A. Carr, Alykhan F. Shamji, Andrew M. Stern and Stuart L. Schreiber agree with the Retraction. Authors Lakshmi Raj, Takao Ide, Aditi U. Gurkar, Anna Mandinova and Sam W. Lee disagree with the Retraction. Author Xiaoyu Li did not respond.

References

  1. 1.

    Raj, L. et al. Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature 481, 534 (2012).

  2. 2.

    Raj, L. et al. Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature 526, 596 (2015).

Download references

Author information

Affiliations

  1. Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA

    • Lakshmi Raj
    • , Takao Ide
    • , Aditi U. Gurkar
    • , Anna Mandinova
    •  & Sam W. Lee
  2. Broad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA

    • Michael Foley
    • , Monica Schenone
    • , Xiaoyu Li
    • , Nicola J. Tolliday
    • , Todd R. Golub
    • , Steven A. Carr
    • , Alykhan F. Shamji
    • , Andrew M. Stern
    • , Anna Mandinova
    • , Stuart L. Schreiber
    •  & Sam W. Lee

Authors

  1. Search for Lakshmi Raj in:

  2. Search for Takao Ide in:

  3. Search for Aditi U. Gurkar in:

  4. Search for Michael Foley in:

  5. Search for Monica Schenone in:

  6. Search for Xiaoyu Li in:

  7. Search for Nicola J. Tolliday in:

  8. Search for Todd R. Golub in:

  9. Search for Steven A. Carr in:

  10. Search for Alykhan F. Shamji in:

  11. Search for Andrew M. Stern in:

  12. Search for Anna Mandinova in:

  13. Search for Stuart L. Schreiber in:

  14. Search for Sam W. Lee in:

Corresponding authors

Correspondence to Anna Mandinova or Stuart L. Schreiber or Sam W. Lee.

About this article

Publication history

Published

DOI

https://doi.org/10.1038/s41586-018-0284-y

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.