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AI in prostate MRI: enhancing accuracy and reducing overdiagnosis

Artificial intelligence can be leveraged to improve the detection of prostate cancer on magnetic resonance imaging; however, before this technology is implemented in clinical practice, further research is required.

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References

  1. Siegel, R. L., Giaquinto, A. N. & Jemal, A. Cancer statistics, 2024. CA Cancer J. Clin. 74, 12–49 (2024).

    Article  PubMed  Google Scholar 

  2. Padhani, A. R. et al. PI-RADS Steering Committee: the PI-RADS multiparametric MRI and MRI-directed biopsy pathway. Radiology 292, 464–474 (2019).

    Article  PubMed  Google Scholar 

  3. Turkbey, B. et al. Multiparametric prostate magnetic resonance imaging in the evaluation of prostate cancer. CA Cancer J. Clin. 66, 326–336 (2016).

    Article  PubMed  Google Scholar 

  4. Kasivisvanathan, V. et al. MRI-targeted or standard biopsy for prostate-cancer diagnosis. N. Engl. J. Med. 378, 1767–1777 (2018).

    Article  PubMed  PubMed Central  Google Scholar 

  5. Turkbey, B. & Oto, A. Factors impacting performance and reproducibility of PI-RADS. Can. Assoc. Radiol. J. 72, 337–338 (2021).

    Article  PubMed  Google Scholar 

  6. Lin, Y., Yilmaz, E. C., Belue, M. J. & Turkbey, B. Prostate MRI and image quality: it is time to take stock. Eur. J. Radiol. 161, 110757 (2023).

    Article  PubMed  PubMed Central  Google Scholar 

  7. Turkbey, B. et al. Prostate Imaging Reporting and Data System version 2.1: 2019 update of Prostate Imaging Reporting and Data System version 2. Eur. Urol. 76, 340–351 (2019).

    Article  PubMed  Google Scholar 

  8. Westphalen, A. C. et al. Variability of the positive predictive value of PI-RADS for prostate MRI across 26 centers: experience of the Society of Abdominal Radiology prostate cancer disease-focused panel. Radiology 296, 76–84 (2020).

    Article  PubMed  Google Scholar 

  9. Belue, M. J. & Turkbey, B. Tasks for artificial intelligence in prostate MRI. Eur. Radiol. Exp. 6, 33 (2022).

    Article  PubMed  PubMed Central  Google Scholar 

  10. Saha, A. et al. Artificial intelligence and radiologists in prostate cancer detection on MRI (PI-CAI): an international, paired, non-inferiority, confirmatory study. Lancet Oncol 25, 879–887 (2024).

    Article  CAS  PubMed  Google Scholar 

Download references

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Correspondence to Baris Turkbey.

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Competing interests

B.T. declares a Cooperative Research and Development Agreement (CRADA) with Philips and NVIDIA, royalties from the National Institutes of Health and patents in the field of artificial intelligence.

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Turkbey, B. AI in prostate MRI: enhancing accuracy and reducing overdiagnosis. Nat Rev Urol (2024). https://doi.org/10.1038/s41585-024-00940-5

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