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Prostate cancer

Single-cell analysis of advanced prostate cancer

Nature Reviews Urology volume 21, page 517 (2024)Cite this article

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Single-cell analysis of treatment-resistant prostate cancer demonstrated high heterogeneity between cell states across various advanced disease types, including castration-resistant and neuroendocrine prostate cancers. Expression of PSMA, STEAP1, STEAP2, TROP2, CEACAM5 and DLL3 were observed to vary within a subset of gene regulatory networks. Thus, gene regulatory networks could be used to identify cell states, which might improve diagnostic precision.

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  1. Nature Reviews Urology http://www.nature.com/nrurol/

    Louise Lloyd

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  1. Louise Lloyd
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Correspondence to Louise Lloyd.

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Lloyd, L. Single-cell analysis of advanced prostate cancer. Nat Rev Urol 21, 517 (2024). https://doi.org/10.1038/s41585-024-00933-4

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