Positive surgical margins are an independent risk factor for biochemical recurrence after radical prostatectomy. However, the identification of residual cancer by eye is highly limited, and frozen sections are not always available or possible for all margins. Prostate-specific membrane antigen-targeted fluorescence guidance might close this gap and enhance the surgeon’s eye.
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The authors declare no competing interests.
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Falkenbach, F., Maurer, T. PSMA-targeted fluorescence guidance for robotic-assisted prostatectomy. Nat Rev Urol 20, 704–705 (2023). https://doi.org/10.1038/s41585-023-00817-z