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PROSTATE CANCER

Nature versus nurture contribution to prostate cancer risk

Nature Reviews Urology volume 19, pages 635–636 (2022)Cite this article

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Genetics has a role in predisposition towards prostate cancer, and an accurate prediction of prostate cancer risk can be made using polygenic risk scores. New evidence suggests that this risk is modifiable through lifestyle changes, but only in men at a high genetic risk of developing prostate cancer.

Refers to Plym, A. et al. A healthy lifestyle in men at increased genetic risk for prostate cancer. Eur. Urol. https://doi.org/10.1016/j.eururo.2022.05.008 (2022).

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Authors and Affiliations

  1. Department of Surgery, Division of Urology and Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA

    Stephen J. Freedland & Nadine (Adriana) Friedrich

  2. Department of Surgery, Section of Urology, Durham VA Medical Center, Durham, NC, USA

    Stephen J. Freedland

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  1. Stephen J. Freedland
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  2. Nadine (Adriana) Friedrich
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Correspondence to Stephen J. Freedland.

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The authors declare no competing interests.

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Freedland, S.J., Friedrich, N.(. Nature versus nurture contribution to prostate cancer risk. Nat Rev Urol 19, 635–636 (2022). https://doi.org/10.1038/s41585-022-00650-w

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  • DOI: https://doi.org/10.1038/s41585-022-00650-w

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