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Nature versus nurture contribution to prostate cancer risk

Genetics has a role in predisposition towards prostate cancer, and an accurate prediction of prostate cancer risk can be made using polygenic risk scores. New evidence suggests that this risk is modifiable through lifestyle changes, but only in men at a high genetic risk of developing prostate cancer.

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Correspondence to Stephen J. Freedland.

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Freedland, S.J., Friedrich, N.(. Nature versus nurture contribution to prostate cancer risk. Nat Rev Urol 19, 635–636 (2022).

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