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MALE FACTOR INFERTILITY

How to select ICSI-viable sperm from the most challenging samples

Nature Reviews Urology volume 19, pages 135–136 (2022)Cite this article

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Sperm characteristics are routinely assessed in fertility clinics as decisive factors to select sperm for improved intracytoplasmic sperm injection (ICSI) outcomes. A recent study suggests that, in patients with non-obstructive azoospermia, no specific defect or combination of abnormalities in testicular sperm precluded chance of pregnancy, while also suggesting sperm motility and acrosome defects are the proxies relevant to ICSI outcomes.

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Fig. 1: Machine learning algorithm-based testicular sperm selection.

References

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Authors and Affiliations

  1. Department of Mechanical and Aerospace Engineering, Monash University, Clayton Campus, Melbourne, Victoria, Australia

    Reza Nosrati

  2. Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, Ontario, Canada

    David Sinton

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  1. Reza Nosrati
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  2. David Sinton
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Correspondence to Reza Nosrati or David Sinton.

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The authors declare no competing interests.

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Nosrati, R., Sinton, D. How to select ICSI-viable sperm from the most challenging samples. Nat Rev Urol 19, 135–136 (2022). https://doi.org/10.1038/s41585-021-00546-1

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