A striking disproportionate burden of prostate cancer incidence and mortality exists between men of West African ancestry and men of European ancestry. Identifying distinct tumour genetic biomarkers and immunomodulating signals in patients with diverse genetic ancestry might reduce the disparities in prostate cancer prognosis, treatment outcomes and mortality in high-risk racial groups.
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Johnson, J.R., Kittles, R.A. Genetic ancestry and racial differences in prostate tumours. Nat Rev Urol 19, 133–134 (2022). https://doi.org/10.1038/s41585-021-00544-3
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DOI: https://doi.org/10.1038/s41585-021-00544-3
