Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Comment
  • Published:

Establishing the Bladder Cancer Research Centre at the University of Birmingham

The new Bladder Cancer Research Centre at the University of Birmingham unifies the university’s multidisciplinary bladder cancer research activity within a single research centre, working within five core research themes to translate biomedical science into health-care benefits for patients with bladder cancer.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Antoni, S. et al. Bladder cancer incidence and mortality: a global overview and recent trends. Eur. Urol. 71, 96–108 (2017).

    Article  Google Scholar 

  2. Babjuk, M. et al. European Association of Urology guidelines on non-muscle-invasive bladder cancer (TaT1 and carcinoma in situ) - 2019 update. Eur. Urol. 76, 639–657 (2019).

    Article  CAS  Google Scholar 

  3. Sylvester, R. J. et al. European Association of Urology (EAU) prognostic factor risk groups for non-muscle-invasive bladder cancer (NMIBC) incorporating the WHO 2004/2016 and WHO 1973 classification systems for grade: an update from the EAU NMIBC Guidelines Panel. Eur. Urol. https://doi.org/10.1016/j.eururo.2020.12.033 (2021).

    Article  PubMed  Google Scholar 

  4. Witjes, J. A. et al. European Association of Urology guidelines on muscle-invasive and metastatic bladder cancer: summary of the 2020 guidelines. Eur. Urol. 79, 82–104 (2021).

    Article  CAS  Google Scholar 

  5. Mostafid, H. et al. Transurethral resection of bladder tumour: the neglected procedure in the technology race in bladder cancer. Eur. Urol. 77, 669–670 (2020).

    Article  Google Scholar 

  6. Bryan, R. T., Kirby, R., O’Brien, T. & Mostafid, H. So much cost, such little progress. Eur. Urol. 66, 263–264 (2014).

    Article  Google Scholar 

  7. Mostafid, A. H., Palou Redorta, J., Sylvester, R. & Witjes, J. A. Therapeutic options in high-risk non-muscle-invasive bladder cancer during the current worldwide shortage of bacille Calmette-Guerin. Eur. Urol. 67, 359–360 (2015).

    Article  Google Scholar 

  8. Bryan, R. et al. Comparing an image-guided pathway with the standard pathway for staging muscle-invasive bladder cancer: preliminary data from the BladderPath study. Eur. Urol. https://doi.org/10.1016/j.eururo.2021.02.021 (2021).

    Article  PubMed  Google Scholar 

  9. Bessa, A. et al. Consensus in bladder cancer research priorities between patients and healthcare professionals using a four-stage modified Delphi method. Eur. Urol. 76, 258–259 (2019).

    Article  Google Scholar 

  10. Kadri, H. et al. Aryloxy diester phosphonamidate prodrugs of phosphoantigens (ProPAgens) as potent activators of Vγ9/Vδ2 T-cell immune responses. J. Med. Chem. 63, 11258–11270 (2020).

    Article  CAS  Google Scholar 

Download references

Acknowledgements

Philanthropic donations to the University of Birmingham in support of bladder cancer research greatly facilitated the establishment of the Bladder Cancer Research Centre (BCRC). The authors also gratefully acknowledge the contributions made by the University of Birmingham’s Human Biomaterials Resource Centre supported through Birmingham Science City — Experimental Medicine Network of Excellence project. They are thankful to the urologists and urology nurses of the West Midlands for their considerable contributions to the recruitment and follow-up of bladder cancer study participants. They are grateful to KK Cheng for his initiation of the Bladder Cancer Prognosis Programme, D. M. A. Wallace and N. D. James for their mentorship, and D. H. Adams and P. R. Kearns for their support of the BCRC. A. Knight, Chairman of Trustees of the charity Action Bladder Cancer UK, provided a critical review of the manuscript.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Richard T. Bryan.

Ethics declarations

Competing interests

R.T.B. has contributed to advisory boards for Olympus Medical Systems and Janssen, and undertakes research funded by UroGen Pharma, QED Therapeutics and Janssen. The other authors declare no competing interests.

Additional information

Related links

Bladder Cancer Research Centre (BCRC): https://www.birmingham.ac.uk/research/bladder-cancer/index.aspx

Cancer Research UK Clinical Trials Unit (CRCTU): https://www.birmingham.ac.uk/research/crctu/index.aspx

University of Birmingham Clinical Trials Unit (BCTU): https://www.birmingham.ac.uk/research/bctu/index.aspx

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Bryan, R.T., Arnold, R., Khanim, F.L. et al. Establishing the Bladder Cancer Research Centre at the University of Birmingham. Nat Rev Urol 18, 318–320 (2021). https://doi.org/10.1038/s41585-021-00448-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41585-021-00448-2

Search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer