New technical modifications enable transperineal prostate biopsy to be performed in the ambulatory setting under local anaesthesia. Although a variety of techniques for administration of local anaesthetic during transperineal prostate biopsy have been described, no consensus exists regarding the most effective method to use. Thus, ample opportunity exists for procedural innovation and future study on this topic.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Pilatz, A. et al. European Association of Urology position paper on the prevention of infectious complications following prostate biopsy. Eur. Urol. 79, 11–15 (2021).
Bhanji, Y., Allaway, M. J. & Gorin, M. A. Recent advances and current role of transperineal prostate biopsy. Urol. Clin. North Am. 48, 25–33 (2021).
Stefanova, V. et al. Transperineal prostate biopsies using local anesthesia: experience with 1,287 patients. Prostate cancer detection rate, complications and patient tolerability. J. Urol. 201, 1121–1126 (2019).
Kum, F. et al. Initial outcomes of local anaesthetic freehand transperineal prostate biopsies in the outpatient setting. BJU Int. 125, 244–252 (2020).
Frank, S. G. & Lalonde, D. H. How acidic is the lidocaine we are injecting, and how much bicarbonate should we add? Can. J. Plast. Surg. 20, 71–73 (2012).
Iremashvili, V. V. et al. Periprostatic local anesthesia with pudendal block for transperineal ultrasound-guided prostate biopsy: a randomized trial. Urology 75, 1023–1027 (2010).
Wang, H. et al. A novel perineal nerve block approach for transperineal prostate biopsy: an anatomical analysis-based randomized single-blind controlled trial. Urology 146, 25–31 (2020).
Kubo, Y. et al. Simple and effective local anesthesia for transperineal extended prostate biopsy: application to three-dimensional 26-core biopsy. Int. J. Urol. 16, 420–423 (2009).
Lv, Z. et al. Efficacy and safety of periprostatic nerve block combined with perineal subcutaneous anaesthesia and intrarectal lidocaine gel in transrectal ultrasound guided transperineal prostate biopsy: a prospective randomised controlled trial. Prostate Cancer Prostatic Dis. 23, 74–80 (2020).
Smith, J. B. et al. Transperineal sector prostate biopsies: a local anesthetic outpatient technique. Urology 83, 1344–1349 (2014).
Acknowledgements
J.C.H. receives research support from the Frederick J. and Theresa Dow Wallace Fund of the New York Community Trust.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
M.J.A. is the founder and owner of Perineologic. M.A.G. is a paid consultant for bk Medical, KOELIS and Perineologic. All other authors declare no competing interests.
Rights and permissions
About this article
Cite this article
Basourakos, S.P., Allaway, M.J., Ross, A.E. et al. Local anaesthetic techniques for performing transperineal prostate biopsy. Nat Rev Urol 18, 315–317 (2021). https://doi.org/10.1038/s41585-021-00443-7
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41585-021-00443-7
This article is cited by
-
Should Transperineal Prostate Biopsy Be the Standard of Care?
Current Urology Reports (2023)