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PROSTATE CANCER

Using hormone therapy with salvage radiotherapy according to presalvage PSA levels

A subgroup analysis of the RTOG 9601 trial, which stratified participants according to their pretreatment serum PSA levels, suggests disparate responses to therapy and potentially concerning cardiac and neurological effects in some men. However, subgroup analyses are notoriously difficult to interpret and the data should be considered with caution before changes are made to clinical practice.

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Correspondence to Alan Dal Pra.

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Dal Pra, A., Pollack, A. Using hormone therapy with salvage radiotherapy according to presalvage PSA levels. Nat Rev Urol 17, 489–490 (2020). https://doi.org/10.1038/s41585-020-0333-9

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