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MRI-guided active surveillance in prostate cancer: not yet ready for practice

Nature Reviews Urology volume 18, pages 77–78 (2021)Cite this article

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Multiparametric MRI enables early detection of progression and reclassification in patients with low-risk prostate cancer on active surveillance and offers the potential to reduce unnecessary biopsies. However, the reliability and reproducibility of MRI-directed surveillance during follow-up is unclear. A recent study highlights the potential and current shortcomings of this approach.

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References

  1. Bokhorst, L. P. et al. A decade of active surveillance in the PRIAS Study: an update and evaluation of the criteria used to recommend a switch to active treatment. Eur. Urol. 70, 954–960 (2016).

    Article  Google Scholar 

  2. Lantz, A. et al. Expanding active surveillance inclusion criteria: a novel nomogram including preoperative clinical parameters and magnetic resonance imaging findings. Eur. Urol. Oncol. 357, 1–8 (2020).

    Google Scholar 

  3. Fujihara, A. et al. Multiparametric magnetic resonance imaging facilitates reclassification during active surveillance for prostate cancer. BJU Int. https://doi.org/10.1111/bju.15272 (2020).

    Article  PubMed  Google Scholar 

  4. Moore, C. M. et al. Reporting magnetic resonance imaging in men on active surveillance for prostate cancer: the PRECISE recommendations-a report of a European School of Oncology task force. Eur. Urol. 71, 648–655 (2017).

    Article  Google Scholar 

  5. Giganti, F. et al. Natural history of prostate cancer on active surveillance: stratification by MRI using the PRECISE recommendations in a UK cohort. Eur. Radiol. https://doi.org/10.1007/s00330-020-07256-z (2020).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Klotz, L. et al. Randomized study of systematic biopsy versus magnetic resonance imaging and targeted and systematic biopsy in men on active surveillance (ASIST): 2-year postbiopsy follow-up. Eur. Urol. 77, 311–317 (2020).

    Article  Google Scholar 

  7. Ploussard, G. et al. Added value of concomitant systematic and fusion targeted biopsies for grade group prediction based on radical prostatectomy final pathology on positive magnetic resonance imaging. J. Urol. 202, 1182–1187 (2019).

    Article  Google Scholar 

  8. Ploussard, G. et al. Active surveillance eligibility of MRI-positive patients with grade group 2 prostate cancer: a pathological study. World J. Urol. 38, 1735–1740 (2020).

    Article  Google Scholar 

  9. Stavrinides, V. et al. Five-year outcomes of magnetic resonance imaging-based active surveillance for prostate cancer: a large cohort study. Eur. Urol. 78, 443–451 (2020).

    Article  CAS  Google Scholar 

  10. Chesnut, G. T. et al. Role of changes in magnetic resonance imaging or clinical stage in evaluation of disease progression for men with prostate cancer on active surveillance. Eur. Urol. 77, 501–507 (2020).

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Urology, La Croix du Sud Hospital, Quint Fonsegrives, France

    Guillaume Ploussard

  2. Department of Radiology, Pitié-Salpétrière Hospital, Paris-Sorbonne University, Paris, France

    Raphaële Renard-Penna

Authors
  1. Guillaume Ploussard
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  2. Raphaële Renard-Penna
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Correspondence to Guillaume Ploussard.

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The authors declare no competing interests

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EAU prostate cancer treatment guidelines: https://uroweb.org/guideline/prostate-cancer/?type=summary-of-changes

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Ploussard, G., Renard-Penna, R. MRI-guided active surveillance in prostate cancer: not yet ready for practice. Nat Rev Urol 18, 77–78 (2021). https://doi.org/10.1038/s41585-020-00416-2

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