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Innovative device illuminates the horizon of bioelectronic medicines

The use of optogenetic strategies in biomedicine therapeutics has the potential to provide nonpharmacological modulation of nervous system function. The development of integrative, implantable, remote-powered devices is an advance towards translation of these strategies, with the potential for precision, revolutionary treatment of complex or refractory disease-related or trauma-related symptoms.

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Fig. 1: Schematic of a fully implantable, soft optoelectronic system for wireless, closed-loop optogenetic modulation of bladder function.


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Correspondence to Warren M. Grill or Jennifer J. DeBerry.

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The authors declare no competing interests.

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Grill, W.M., DeBerry, J.J. Innovative device illuminates the horizon of bioelectronic medicines. Nat Rev Urol 16, 209–210 (2019).

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