A large genomic study of upper tract urothelial carcinoma and bladder tumours reveals differences in mutational frequencies and demonstrates a clonal relationship between paired tumours. In addition to these genomic insights, a combined tumour and germline genetic analysis approach is suggested to improve the identification of patients with Lynch syndrome.
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Dyrskjøt, L. Large-scale genomic comparison of UTUC and bladder tumours. Nat Rev Urol 16, 149–150 (2019). https://doi.org/10.1038/s41585-019-0145-y
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DOI: https://doi.org/10.1038/s41585-019-0145-y
