Risk of solid cancer after chemotherapy

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Platinum-based chemotherapy continues to be linked with the subsequent development of various solid tumours. In a large analytical study of >5,800 survivors of testicular cancer, Groot and colleagues observed statistically significant dose-dependent increases in gastrointestinal cancer incidence after platinum-based chemotherapy, providing evidence for a potential dose-dependent relationship.

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L.B.T. is supported by grant R01 CA 157823 awarded by the National Cancer Institute.

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Correspondence to Lois B. Travis.

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Fung, C., Travis, L.B. Risk of solid cancer after chemotherapy. Nat Rev Urol 15, 660–661 (2018) doi:10.1038/s41585-018-0085-y

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