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Immunometabolism

Shedding light onto the immunometabolic effects of glucocorticoids

Nature Reviews Rheumatology volume 20, pages 529–530 (2024)Cite this article

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Glucocorticoids are important anti-inflammatory and immunosuppressive drugs and potent regulators of metabolism. However, their immune and metabolic effects have been treated as separate entities. New research is shedding light onto the intersection between the immunoregulatory and metabolic effects of glucocorticoids.

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Fig. 1: Anti-inflammatory action of glucocorticoids in mice involves metabolites of the tricarboxylic acid cycle.

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Authors and Affiliations

  1. Functional Immunogenomics Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA

    Luis M. Franco

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  1. Luis M. Franco
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Correspondence to Luis M. Franco.

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The author declares no competing interests.

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Franco, L.M. Shedding light onto the immunometabolic effects of glucocorticoids. Nat Rev Rheumatol 20, 529–530 (2024). https://doi.org/10.1038/s41584-024-01144-2

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