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A nosology of immune diseases from deep immunophenotyping

In 2006, a linear immunological continuum of autoinflammatory and autoimmune disorders ranging from monogenic diseases of innate immunity at one end to monogenic diseases of adaptive immunity at the other end was proposed to classify these conditions. Deep immunophenotyping has now revealed a cell-based nosology of these disorders.

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Fig. 1: Multiple interwoven and interlinked levels of complexity in rheumatoid arthritis (RA) pathogenesis.


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Correspondence to Michael F. McDermott.

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McDermott, M.F. A nosology of immune diseases from deep immunophenotyping. Nat Rev Rheumatol 20, 256–257 (2024).

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