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Psoriatic arthritis

Bimekizumab safe and effective for psoriatic arthritis

Nature Reviews Rheumatology volume 19, page 64 (2023)Cite this article

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Dual inhibition of IL-17A and IL-17F with bimekizumab leads to superior improvements in joint and skin outcomes compared with placebo in patients with active psoriatic arthritis who are either naive to biologic DMARDs or who have had a previous inadequate response or intolerance to TNF inhibition, according to results from the BE OPTIMAL and BE COMPLETE phase III clinical trials. At 16 weeks, more patients reached an ACR50 response in the treatment groups than in the placebo groups (44% versus 10% for the BE OPTIMAL trial; 43% versus 7% for the BE COMPLETE trial). The safety profile of bimekizumab was consistent with previous reports.

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  1. Nature Reviews Rheumatology http://www.nature.com/nrrheum/

    Jessica McHugh

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  1. Jessica McHugh
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Correspondence to Jessica McHugh.

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McHugh, J. Bimekizumab safe and effective for psoriatic arthritis. Nat Rev Rheumatol 19, 64 (2023). https://doi.org/10.1038/s41584-022-00903-3

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  • DOI: https://doi.org/10.1038/s41584-022-00903-3

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