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Systemic lupus erythematosus

Gene-expression profiles predict rituximab response in SLE

Nature Reviews Rheumatology volume 19, page 63 (2023)Cite this article

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New research shows that the ancestry of patients with systemic lupus erythematosus (SLE) is associated with blood gene-expression signatures and can predict the response to B cell depletion by rituximab.

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References

Original article

  • Carter, L. M. et al. Gene expression and autoantibody analysis reveals distinct ancestry-specific profiles associated with response to rituximab in refractory systemic lupus erythematosus. Arthritis Rheumatol. https://doi.org/10.1002/art.42404 (2022)

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  1. Nature Reviews Rheumatology http://www.nature.com/nrrheum/

    Robert Phillips

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  1. Robert Phillips
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Correspondence to Robert Phillips.

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Phillips, R. Gene-expression profiles predict rituximab response in SLE. Nat Rev Rheumatol 19, 63 (2023). https://doi.org/10.1038/s41584-022-00897-y

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  • DOI: https://doi.org/10.1038/s41584-022-00897-y

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