Built by and for the research community, the Musculoskeletal Knowledge Portal (MSK-KP) offers researchers a single integrated platform on which to display, access, distill and explore results from large genomic and epigenomic studies to formulate hypotheses and accelerate the development of patient-centered therapeutics for complex, multi-factorial conditions such as osteoarthritis.
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Genetics implicates overactive osteogenesis in the development of diffuse idiopathic skeletal hyperostosis
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D.P.K. declares he has received grant funding to his institution from Amgen, Radius Health and Solarea Bio; serves on scientific advisory boards for Pfizer and Solarea Bio; and has received royalties for publication in UpToDate from Wolters Kluwer. The other authors declare no competing interests.
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Related links
Bonebase: https://bonebase.lab.uconn.edu/
Genetics of Osteoarthritis Consortium: https://www.genetics-osteoarthritis.com/
Human Cell Atlas: https://www.humancellatlas.org/
International Federation of Musculoskeletal Research Societies: https://www.ifmrs.org/
Knowledge Portal Network: https://kp4cd.org/
Musculoskeletal Knowledge Portal: https://msk.hugeamp.org/
Single Cell Portal: https://singlecell.broadinstitute.org/single_cell
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Westendorf, J.J., Bonewald, L.F., Kiel, D.P. et al. The Musculoskeletal Knowledge Portal: improving access to multi-omics data. Nat Rev Rheumatol 18, 1–2 (2022). https://doi.org/10.1038/s41584-021-00711-1
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DOI: https://doi.org/10.1038/s41584-021-00711-1
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