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OSTEOARTHRITIS

Going for gold to improve anti-NGF therapy in OA

Nature Reviews Rheumatology volume 17, page 508 (2021)Cite this article

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The development of agents that target nerve growth factor (NGF) as a treatment for osteoarthritis (OA) has not been a smooth process. Associations between anti-NGF antibody therapy and rapidly progressive OA have prompted research into alternative approaches to target NGF that have improved safety profiles. A new study published in ACS Nano is championing one such approach: antibody-directed photothermal therapy.

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  • Wise, B. L. et al. The evolution of nerve growth factor inhibition in clinical medicine. Nat. Rev. Rheumatol. 17, 34–46 (2021)

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  1. Nature Reviews Rheumatology http://www.nature.com/nrrheum/

    Joanna Clarke

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  1. Joanna Clarke
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Correspondence to Joanna Clarke.

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Clarke, J. Going for gold to improve anti-NGF therapy in OA. Nat Rev Rheumatol 17, 508 (2021). https://doi.org/10.1038/s41584-021-00670-7

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  • DOI: https://doi.org/10.1038/s41584-021-00670-7

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