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CLINICAL TRIALS

Striking a balance in rheumatoid arthritis prevention trials

Nature Reviews Rheumatology volume 17, pages 385–386 (2021)Cite this article

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The discovery that autoantibodies and other factors can predict the future onset of rheumatoid arthritis (RA) has encouraged the development of clinical trials looking at RA prevention. Although an exciting area of research, finding an approach that results in the successful completion of an RA prevention trial is challenging.

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Fig. 1: Balancing factors related to study design and participation in RA prevention trials.

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Authors and Affiliations

  1. Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada

    Liam J. O’Neil

  2. University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA

    Kevin D. Deane

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  1. Liam J. O’Neil
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  2. Kevin D. Deane
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Correspondence to Kevin D. Deane.

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The authors declare no competing interests.

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O’Neil, L.J., Deane, K.D. Striking a balance in rheumatoid arthritis prevention trials. Nat Rev Rheumatol 17, 385–386 (2021). https://doi.org/10.1038/s41584-021-00627-w

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