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STEM CELLS

Streamlining cell fate decisions during chondrogenesis

Nature Reviews Rheumatology volume 17, pages 313–314 (2021)Cite this article

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The accurate homogeneous differentiation of human induced pluripotent stem cells into chondrocytes is crucial for cartilage regenerative therapies. Discovery of the signalling pathways responsible for the differentiation of unwanted cell types during in vitro chondrogenesis could herald a breakthrough for in vitro cartilage generation.

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Fig. 1: Improving the quality of human induced pluripotent stem cell-derived chondrocytes.

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Authors and Affiliations

  1. CiSTEM Laboratory, Catholic iPSC Research Center, College of Medicine, The Catholic University of Korea, Seoul, South Korea

    Yeri Alice Rim & Ji Hyeon Ju

  2. Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea

    Ji Hyeon Ju

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  1. Yeri Alice Rim
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  2. Ji Hyeon Ju
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Correspondence to Ji Hyeon Ju.

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The authors declare no competing interests.

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Rim, Y.A., Ju, J.H. Streamlining cell fate decisions during chondrogenesis. Nat Rev Rheumatol 17, 313–314 (2021). https://doi.org/10.1038/s41584-021-00604-3

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