An analysis of data from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis (BSRBR-RA) identified distinct patterns of response in patients with RA who began anti-TNF treatment between 2001 and 2013. The trajectories of treatment response were apparent within a few months of treatment initiation and reflected long-term outcomes. In a four-class model, most patients in the study followed a ‘modest’ (55.3%) or ‘substantial’ (32.4%) response trajectory, with 8.7% of the patients fitting the ‘maximal’ response trajectory (corresponding to sustained remission) and 3.6% the ‘minimal’ response trajectory.
References
Original article
Hamann, P. D. H. et al. Early response to anti-TNF predicts long-term outcomes including sustained remission: an analysis of the BSRBR-RA. Rheumatology https://doi.org/10.1093/rheumatology/kez518 (2019)
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Onuora, S. Long-term response in RA apparent by 6 months. Nat Rev Rheumatol 16, 2 (2020). https://doi.org/10.1038/s41584-019-0345-0
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41584-019-0345-0