The global burden of musculoskeletal diseases increased significantly between the years 2000 and 2015, as measured by the disability-adjusted life years index (P < 0.001), and is higher in Europe than in all other continents. Over the same period, musculoskeletal diseases remained the second leading cause of years lived with disability worldwide.
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Sebbag, E. et al. The world-wide burden of musculoskeletal diseases: a systematic analysis of the World Health Organization Burden of Diseases Database. Ann. Rheum. Dis. https://doi.org/10.1136/annrheumdis-2019-215142 (2019)
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Onuora, S. Burden of musculoskeletal diseases increasing. Nat Rev Rheumatol 15, 318 (2019). https://doi.org/10.1038/s41584-019-0232-8
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DOI: https://doi.org/10.1038/s41584-019-0232-8