Antibodies against phosphatidylserine–prothrombin complexes (PS–PT) are one type of antiphospholipid antibody that is responsible for lupus anticoagulant activity. Anti-PS–PT antibodies are not currently included in the classification criteria for antiphospholipid syndrome (APS), but should they replace lupus anticoagulant testing to improve the diagnosis of APS?
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Fujieda, Y., Atsumi, T. Has lupus anticoagulant testing had its day?. Nat Rev Rheumatol 15, 324–325 (2019). https://doi.org/10.1038/s41584-019-0218-6
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DOI: https://doi.org/10.1038/s41584-019-0218-6