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RHEUMATOID ARTHRITIS

Could IL-6 inhibition prevent exercise-induced fat loss in RA?

Nature Reviews Rheumatology volume 15, pages 192–194 (2019)Cite this article

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New research indicates that tocilizumab limits the beneficial effects of exercise on abdominal fat loss. What does this mean for patients with chronic disease who are being treated with tocilizumab or other inhibitors of IL-6 signalling?

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Fig. 1: Exercise and IL-6 inhibition in rheumatoid arthritis.

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Authors and Affiliations

  1. Carnegie School of Sports, Leeds Beckett University, Headingley Campus, Leeds, UK

    Antonios Stavropoulos-Kalinoglou

  2. Clinical Research Unit, Russells Hall Hospital, Dudley Hospitals NHS Foundation Trust, Dudley, UK

    George D. Kitas

  3. Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, UK

    George D. Kitas

Authors
  1. Antonios Stavropoulos-Kalinoglou
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  2. George D. Kitas
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Correspondence to George D. Kitas.

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The authors declare no competing interests.

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Stavropoulos-Kalinoglou, A., Kitas, G.D. Could IL-6 inhibition prevent exercise-induced fat loss in RA?. Nat Rev Rheumatol 15, 192–194 (2019). https://doi.org/10.1038/s41584-019-0189-7

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