Although neuroscientists focus on only very few animal species today, there are many important reasons to take advantage of model system diversity and embrace (anew) a comparative approach in modern brain research. Recent technological advances make this increasingly possible.
This is a preview of subscription content, access via your institution
Open Access articles citing this article.
Nature Open Access 30 August 2023
Scientific Reports Open Access 02 September 2022
Cell and Tissue Research Open Access 23 January 2021
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Rent or buy this article
Prices vary by article type
Prices may be subject to local taxes which are calculated during checkout
Albright, T. & Squire, L. R. (eds) The History of Neuroscience in Autobiography Vols 1–10 (Society for Neuroscience, 2018).
Dobzhansky, T. Nothing in biology makes sense except in the light of evolution. Am. Biol. Teach. 35, 125–129 (1973).
Moran, Y. et al. Evolution of voltage-gated ion channels at the emergence of Metazoa. J. Exp. Biol. 218, 515–25 (2015).
Burkhardt, P. The origin and evolution of synaptic proteins — choanoflagellates lead the way. J. Exp. Biol. 218, 506–514 (2015).
Wilson, D. W. et al. A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast. Nature 339, 355–359 (1989).
Holland, N. D. Early central nervous system evolution: an era of skin brains? Nat. Rev. Neurosci. 4, 617–627 (2003).
Wang, Z., Gerstein, M. & Snyder, M. RNA-Seq: a revolutionary tool for transcriptomics. Nat. Rev. Genet. 10, 57–63 (2009).
Lander, E. S. The heroes of CRISPR. Cell 164, 18–28 (2016).
Camhi, J. Neuroethology — Nerve cells and the natural behavior of animals (Sinauer Associates, 1984).
Marder, E., Bucher, D. & Prinz, A. A. Similar network activity from disparate circuit parameters. Nat. Neurosci. 7, 1345–1352 (2004).
The author declares no competing interests.
A Look at NIH Support for Model Organisms, Part Two: https://nexus.od.nih.gov/all/2016/08/03/model-organisms-part-two/
A Look at Trends in NIH’s Model Organism Research Support: https://nexus.od.nih.gov/all/2016/07/14/a-look-at-trends-in-nihs-model-organism-research-support/
IUCN Red List of Ecosystems: https://www.iucn.org/resources/conservation-tools/iucn-red-list-ecosystems
About this article
Cite this article
Laurent, G. On the value of model diversity in neuroscience. Nat Rev Neurosci 21, 395–396 (2020). https://doi.org/10.1038/s41583-020-0323-1
This article is cited by
Scientific Reports (2022)
Nature Reviews Neuroscience (2022)
Cell and Tissue Research (2021)