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Continued access to investigational brain implants

Nature Reviews Neurosciencevolume 19pages317318 (2018) | Download Citation

Brain implants are being trialled for their potential to ameliorate treatment-resistant conditions or to restore function. However, there are no clear guidelines for continued access to brain implants for trial participants whose symptoms improve with these devices.

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The views expressed are those of the authors alone, and do not necessarily reflect views of the NIH or Baylor College of Medicine.

CIOMS/WHO guidelines: https://cioms.ch/wp-content/uploads/2017/01/WEB-CIOMS-EthicalGuidelines.pdf

NBAC report: https://bioethicsarchive.georgetown.edu/nbac/clinical/Vol1.pdf

Belmont Report: https://www.hhs.gov/ohrp/regulations-and-policy/belmont-report/

The Dish: Participants as Partners: https://allofus.nih.gov/news-events-and-media/videos/dish-participants-partners

Participation: https://allofus.nih.gov/about/participation

References

  1. 1.

    Holtzheimer, P. E. et al. Lancet Psychiatry 4, 839–849 (2017).

  2. 2.

    Underwood, E. Science https://doi.org/10.1126/science.aar3698 (2017).

  3. 3.

    Rossi, P. J., Giordano, J. & Okun, M. S. JAMA Neurol. 74, 9–10 (2017).

  4. 4.

    World Medical Association. JAMA 310, 2191–2194 (2013).

  5. 5.

    Richardson, H. S. & Belsky, L. Hastings Cent. Rep. 34, 25–33 (2004).

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Acknowledgements

The authors thank M. Husain and A. Viswanathan for helpful input about issues addressed in this article. Research for this article was funded by the US National Institute of Mental Health (grant R01-MH114854-01 to G.L.M.), the US National Eye Institute (grant R01-EY023336-04 to D.Y.) and the US National Institute of Neurological Disorders and Stroke (grant UH3-NS100549-01 to W.K.G.).

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Affiliations

  1. Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX, USA

    • Gabriel Lázaro-Muñoz
    •  & Amy L. McGuire
  2. Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA

    • Daniel Yoshor
  3. Departments of Neurosurgery and Neuroscience, Baylor College of Medicine, Houston, TX, USA

    • Michael S. Beauchamp
  4. Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA

    • Wayne K. Goodman

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The authors declare no competing interests.

Corresponding author

Correspondence to Gabriel Lázaro-Muñoz.

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DOI

https://doi.org/10.1038/s41583-018-0004-5

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