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Neurodegenerative disease

WNT receptor variant linked to synaptic degeneration

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Original article

  • Jones, M. E. et al. A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer’s disease. Sci. Adv. 9, eabo7421 (2023)

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Related articles

  • Tzioras, M. et al. Synaptic degeneration in Alzheimer disease. Nat. Rev. Neurol. 19, 19–38 (2023);

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  • De Ferrari, G. V. et al. Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer’s disease. Proc. Natl Acad. Sci. USA 104, 9434–9439 (2007)

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Correspondence to Heather Wood.

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Wood, H. WNT receptor variant linked to synaptic degeneration. Nat Rev Neurol 19, 129 (2023).

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