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Neuropsychiatric symptoms in AD: the search for mechanisms

New work building on the results of genome-wide association studies in Alzheimer disease has identified molecular mechanisms that are shared with some psychiatric disorders. The study leveraged ‘omics data and has the realistic potential to elucidate unknown disease mechanisms; however, a lack of information about neuropsychiatric symptoms in the participants with Alzheimer disease limits the conclusions.

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B.C. and K.L. are supported by the National Institute On Aging of the National Institutes of Health under award number R01AG067015. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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Correspondence to Byron Creese.

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Creese, B., Lunnon, K. Neuropsychiatric symptoms in AD: the search for mechanisms. Nat Rev Neurol 18, 639–640 (2022).

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