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Identifying molecular targets in trigeminal nociception

A new paper published in Neuron presents an analysis of mRNA expression in human and mouse trigeminal ganglia at single-nucleus resolution. The resulting resource is thought-provoking and suggests new targets for pain therapies; however, the findings should be interpreted in the context of the available protein data and warrant functional verification.

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Correspondence to Lars Edvinsson.

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Edvinsson, L., Edvinsson, J.C.A. & Haanes, K.A. Identifying molecular targets in trigeminal nociception. Nat Rev Neurol 18, 385–386 (2022). https://doi.org/10.1038/s41582-022-00671-4

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