The largest genome-wide association study of amyotrophic lateral sclerosis to date has identified new risk loci and provided insight into factors that influence susceptibility to the disease, highlighting the possibility that disease risk and disease progression are influenced by separate factors, with therapeutic implications.
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The authors declare no competing interests.
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Todd, T.W., Petrucelli, L. Amyotrophic lateral sclerosis — insight into susceptibility. Nat Rev Neurol 18, 189–190 (2022). https://doi.org/10.1038/s41582-022-00629-6