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NEURODEGENERATIVE DISEASE

Defining traumatic encephalopathy syndrome — advances and challenges

Chronic traumatic encephalopathy (CTE) is presumed to be associated with a clinical condition termed traumatic encephalopathy syndrome (TES). A new set of research diagnostic criteria for TES might be an improvement over previous guidelines, but many questions surrounding the putative link between head impacts, CTE neuropathology and neurobehavioural symptoms remain unanswered.

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Acknowledgements

The authors thank J. Schaffert, who assisted with the preparation of this commentary.

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Correspondence to C. Munro Cullum.

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Cullum, C.M., LoBue, C. Defining traumatic encephalopathy syndrome — advances and challenges. Nat Rev Neurol 17, 331–332 (2021). https://doi.org/10.1038/s41582-021-00500-0

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