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EPILEPSY

Ultra-high-field MRI improves detection of epileptic lesions

Nature Reviews Neurology volume 16, page 654 (2020)Cite this article

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Ultra-high-field (7 T) MRI with post-processing analysis can increase the probability of detecting an epileptic brain lesion in patients undergoing assessment for epilepsy surgery, according to new research published in Epilepsia. The identification of such a lesion can increase the accuracy of surgical resection, thereby improving seizure outcomes.

“MRI is one of the most useful modalities for delineating the extent of the epileptogenic zone; however, up to 40% of patients undergoing presurgical evaluation have negative or ‘non-lesional’ 3 T clinical MRI,” explains corresponding author Irene Wang. “Surgery in the absence of a visible lesion is currently one of the greatest clinical challenges for tertiary epilepsy centres, and patients with non-lesional MRI tend to have poor seizure outcomes.”

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  • Obusez, E. C. et al. 7 T MR of intracranial pathology: preliminary observations and comparisons to 3 T and 1.5 T. Neuroimage 168, 459–476 (2018)

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  • Zijlmans, M. et al. Changing concepts in presurgical assessment for epilepsy surgery. Nat. Rev. Neurol. 15, 594–606 (2019)

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  1. Nature Reviews Neurology http://www.nature.com/nrneurol/

    Heather Wood

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  1. Heather Wood
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Correspondence to Heather Wood.

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Wood, H. Ultra-high-field MRI improves detection of epileptic lesions. Nat Rev Neurol 16, 654 (2020). https://doi.org/10.1038/s41582-020-00425-0

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