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ALZHEIMER DISEASE

Refining the understanding of typical Alzheimer disease

Understanding the heterogeneity of typical Alzheimer disease (AD) is of increasing importance for the development of new and effective treatments. A new study in patients with AD described two robust cognitive subtypes with different pathology distributions, genetic backgrounds and clinical trajectories.

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Correspondence to Frank Jessen.

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Jessen, F. Refining the understanding of typical Alzheimer disease. Nat Rev Neurol 15, 623–624 (2019). https://doi.org/10.1038/s41582-019-0259-0

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