ALZHEIMER DISEASE

Alzheimer disease risk genes: 29 and counting

The risk of Alzheimer disease is substantially influenced by genetic factors. A new genome-wide association study of more than 600,000 individuals identifies nine novel Alzheimer disease risk genes, raising the total count of independent risk loci to 29.

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Acknowledgements

L.B. is supported by grants from the Deutsche Forschungsgemeinschaft (DFG), the European Research Council (ERC) and the Cure Alzheimer’s Fund (CAF). R.E.T. is supported by the Cure Alzheimer’s Fund and the JPB Foundation.

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Correspondence to Lars Bertram.

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Bertram, L., Tanzi, R.E. Alzheimer disease risk genes: 29 and counting. Nat Rev Neurol 15, 191–192 (2019). https://doi.org/10.1038/s41582-019-0158-4

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