A new analysis has found that concussion and mild traumatic brain injury (mTBI) are linked to an increased risk of suicidal behaviours and thoughts. However, a host of risk factors might influence this correlation, and careful investigation is required to establish which individuals with mTBI might be most at risk of suicide.
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Fralick, M. et al. Association of concussion with the risk of suicide: a systematic review and meta-analysis. JAMA Neurol. https://doi.org/10.1001/jamaneurol.2018.3487 (2018).
Redelmeier, D. A. & Bhatti, J. A. On the link between concussions and suicide. JAMA Neurol. https://doi.org/10.1001/jamaneurol.2018.3445 (2018).
Collins, M. W. et al. A comprehensive, targeted approach to the clinical care of athletes following sport-related concussion. Knee Surg. Sports Traumatol. Arthrosc. 22, 235–246 (2014).
Bahraini, N. & Brenner, L. A. Screening for TBI and persistent symptoms provides opportunities for prevention and intervention. J. Head Trauma Rehabil. 28, 223–226 (2013).
Sampson, R. J. & Laub, J. H. in Developmental Theories of Crime and Delinquency: Advances in Criminological Theory Ch. 4 (ed. Thornberry, T.) (Transaction Publishers, 2004).
Forrest, C. B. & Riley, A. W. Childhood origins of adult health: a basis for life-course health policy. Health Aff. (Millwood) 23, 155–164 (2004).
Brenner, L. A., Vanderploeg, R. D. & Terrio, H. Assessment and diagnosis of mild traumatic brain injury, posttraumatic stress disorder, and other polytrauma conditions: burden of adversity hypothesis. Rehabil. Psychol. 54, 239–246 (2009).
Seguin, M. et al. Life trajectories and burden of adversity: mapping the developmental profiles of suicide mortality. Psychol. Med. 37, 1575–1583 (2007).
O’Rand, A. The precious and the precocious: understanding cumulative disadvantage and cumulative advantage over the life course. Gerontologist 36, 230–238 (1996).
Reid, M. W. et al. Adversity and resilience are associated with outcome after mild traumatic brain injury in military service members. J. Neurotrauma 35, 1146–1155 (2018).
L.A.B. consults for a professional sports league. The views, opinions and findings contained in this article are those of the authors and should not be construed as official Department of Veterans Affairs positions, policies or decisions unless so designated by other documentation.
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Brenner, L.A., Bahraini, N.H. Concussion and risk of suicide: who, when and under what circumstances?. Nat Rev Neurol 15, 132–133 (2019). https://doi.org/10.1038/s41582-019-0136-x