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NEURODEGENERATIVE DISEASE

APOE*ε4 — a risk factor for TDP43 pathology?

Nature Reviews Neurology volume 14, pages 570–571 (2018)Cite this article

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The main genetic risk factor for Alzheimer disease (AD) pathology is also associated with TAR DNA-binding protein 43 (TDP43) proteinopathy, the main pathology in amyotrophic lateral sclerosis and frontotemporal dementia, new research has shown. A possible causal role for TDP43 pathology in hippocampal sclerosis was also identified.

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    Ian Fyfe

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  1. Ian Fyfe
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Correspondence to Ian Fyfe.

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Fyfe, I. APOE*ε4 — a risk factor for TDP43 pathology?. Nat Rev Neurol 14, 570–571 (2018). https://doi.org/10.1038/s41582-018-0064-1

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  • DOI: https://doi.org/10.1038/s41582-018-0064-1

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