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Thiazides in kidney transplant recipients: skin in the game

Clinical trial data suggest that thiazides and thiazide-like drugs could be beneficial for blood-pressure lowering in patients with severe chronic kidney disease. However, prolonged exposure to these photosensitizing drugs could translate into increased risk of squamous cell carcinoma and post-transplant diabetes in the already extremely vulnerable kidney transplant population.

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Fig. 1: The role of thiazides in the development of squamous cell carcinoma after transplantation.


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Correspondence to Steven Van Laecke.

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Nature Reviews Nephrology thanks Peter Conlan and the other, anonymous, reviewer(s) for their contribution to the peer review of this work.

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Van Laecke, S. Thiazides in kidney transplant recipients: skin in the game. Nat Rev Nephrol 20, 351–352 (2024).

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