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Salt substitution: opportunities and challenges for nephrology

Nature Reviews Nephrology volume 18, pages 539–540 (2022)Cite this article

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Salt substitution — the partial replacement of sodium with potassium in table salt — is emerging as a powerful public health strategy to reduce hypertension and related diseases. Here, we explore whether salt substitution is suitable for people with kidney disease by weighing the potential cardiorenal benefits against the risk of hyperkalaemia.

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Fig. 1: Potential benefits and risks of salt substitution in people with CKD.

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Acknowledgements

E.J.H.’s work is supported by the Dutch Kidney Foundation (grant 21OK+13).

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Authors and Affiliations

  1. Department of Internal Medicine, Division of Nephrology and Transplantation, Erasmus Medical Center, Rotterdam, the Netherlands

    Ewout J. Hoorn

  2. The George Institute for Global Health and School of Public Health, University of New South Wales, Sydney, New South Wales, Australia

    Matti Marklund & Jason H. Y. Wu

  3. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA

    Matti Marklund

  4. Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden

    Matti Marklund

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  1. Ewout J. Hoorn
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Correspondence to Ewout J. Hoorn.

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Hoorn, E.J., Marklund, M. & Wu, J.H.Y. Salt substitution: opportunities and challenges for nephrology. Nat Rev Nephrol 18, 539–540 (2022). https://doi.org/10.1038/s41581-022-00599-4

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