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Advancing kidney health justice through gender-affirming care

Advancing kidney health justice for all requires the kidney-care community to embrace gender-affirming care across the life course, including inclusion of gender minority individuals in research, thoughtful attention to sexual-orientation and gender-identity data collection, as well as the promotion of policies and practices that protect and provide comprehensive care to all patients.

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  1. Safer, J. D. & Tangpricha, V. Care of the transgender patient. Ann. Intern. Med. 171, ITC1–ITC16 (2019).

    Article  Google Scholar 

  2. Hembree, W. C. et al. Endocrine treatment of gender-dysphoric/gender-incongruent persons: an Endocrine Society Clinical Practice Guideline. J. Clin. Endocrinol. Metab. 102, 3869–3903 (2017).

    Article  Google Scholar 

  3. Collister, D., Saad, N., Christie, E. & Ahmed, S. Providing care for transgender persons with kidney disease: a narrative review. Can. J. Kidney Health Dis. 8, 2054358120985379 (2021).

    PubMed  PubMed Central  Google Scholar 

  4. Deutsch, M. B. Guidelines for the primary and gender-affirming care of transgender and gender nonbinary people. (2016).

  5. Banks, K. et al. Blood pressure effects of gender-affirming hormone therapy in transgender and gender-diverse adults. Hypertension 77, 2066–2074 (2021).

    CAS  Article  Google Scholar 

  6. Maheshwari, A. et al. The effect of gender-affirming hormone therapy on serum creatinine in transgender individuals. Endocr. Pract. 28, 52–57 (2022).

    Article  Google Scholar 

  7. Tangpricha, V. Gender affirming hormone therapy and risk of diabetes in transgender persons. J. Clin. Endocrinol. Metab. (2022).

  8. Eckenrode, H. E., Gutierrez, O. M., Osis, G., Agarwal, A. & Curtis, L. M. Kidney disease prevalence in transgender individuals. Clin. J. Am. Soc. Nephrol. 17, 280–282 (2022).

    Article  Google Scholar 

  9. Salas-Humara, C., Sequeira, G. M., Rossi, W. & Dhar, C. P. Gender affirming medical care of transgender youth. Curr. Probl. Pediatr. Adolesc. Health Care 49, 100683 (2019).

    Article  Google Scholar 

  10. Tordoff, D. M. et al. Mental health outcomes in transgender and nonbinary youths receiving gender-affirming care. JAMA Netw. Open 5, e220978 (2022).

    Article  Google Scholar 

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Correspondence to Han E. Eckenrode or Dinushika Mohottige.

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The authors declare no competing interests.

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Eckenrode, H.E., Flynn, J.T. & Mohottige, D. Advancing kidney health justice through gender-affirming care. Nat Rev Nephrol 18, 343–344 (2022).

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