Kidney failure is associated with the retention and subsequent accumulation of uraemic toxins, which have detrimental effects on various physiological processes. The removal of these toxins by current dialysis modalities is inadequate, highlighting the need for innovative approaches to enhance their clearance and/or suppress their generation to improve outcomes for patients with kidney disease.
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R.M. has received a grant from Gambro Dialysatoren GmbH (Baxter) for collaborative research and is a member of the ESAO/ERA-EDTA endorsed Work Group EUTox. M.C.V. declares no competing interests.
European Uremic Toxin Work Group: http://www.uremic-toxins.org/
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Masereeuw, R., Verhaar, M.C. Innovations in approaches to remove uraemic toxins. Nat Rev Nephrol 16, 552–553 (2020). https://doi.org/10.1038/s41581-020-0299-0
Nature Reviews Nephrology (2020)