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Glomerular and tubulointerstitial eQTLs for genomic discovery

Nature Reviews Nephrologyvolume 15pages34 (2019) | Download Citation

A new study discovered thousands of expression quantitative trait loci (eQTLs) in the renal glomerular and tubulointerstitial compartments and integrated these data with other omics data sets to identify genes with roles in the pathogenesis of chronic kidney disease. This report reinforces the necessity of using compartment-derived eQTLs to advance kidney genomic discovery.

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Additional information


Human kidney eQTL atlas:


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The author’s work is supported by the Charles Woodson Clinical Research Fund, the Ravitz Foundation and by National Institutes of Health RO1-DK108805.

Author information


  1. Department of Pediatrics-Nephrology, University of Michigan Medical School, Ann Arbor, MI, USA

    • Matthew G. Sampson
  2. Center for Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI, USA

    • Matthew G. Sampson


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The author declares no competing interests.

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Correspondence to Matthew G. Sampson.

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